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Alyssa Milano, December 19
Best known for her breakout role as Samantha Micelli on Who’s the Boss?, the Brooklyn-born actress and activist has gone on to appear regularly on TV for decades, as a lead on Charmed, Insatiable and Mistresses and as the host of Project Runway All Stars. In recent years, she became a vocal supporter of the #MeToo movement, which she helped bring attention to when she shared a story of her own sexual abuse 25 years earlier. Since 2019, she’s hosted the podcast Sorry Not Sorry, and she released an intimate and revealing book of the same name this October.